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Article

Frequency of hepatitis B virus mutant in asymptomatic hepatitis B virus carriers receiving prophylactic lamivudine during chemotherapy for hematologic malignancies.

The hematology journal : the official journal of the European Haematology Association - 1 Jan 2004

Pelizzari Anna Maria, Motta Maddalena, Cariani Elisabetta, Turconi Paola, Borlenghi Erika, Rossi Giuseppe

Abstract excerpt

Hepatitis B virus (HBV) reactivation is a potentially fatal complication of chemotherapy in asymptomatic HBV carriers. Prophylactic lamivudine has proven effective for its prevention, but the potential emergence of lamivudine-resistant HBV YMMD mutants, as shown in patients treated for chronic hepatitis, may limit its use. To evaluate the frequency of HBV YMMD mutant and its clinical significance, we have...

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Identifiers

PMID: 15297849
DOI: 10.1038/sj.thj.6200396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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