Article
Effects of glucose on fsr-mediated biofilm formation in Enterococcus faecalis.
The Journal of infectious diseases - 1 Sept 2004
Pillai Satish K, Sakoulas George, Eliopoulos George M, Moellering Robert C, Murray Barbara E, Inouye Roger T
Abstract excerpt
Biofilm production is frequently dependent on such environmental factors as cell density and glucose concentration. The Enterococcus faecalis quorum-sensing locus (fsr) increases enterococcal virulence in multiple animal models. To date, fsr has been shown to regulate the transcription of 2 downstream protease genes. We demonstrate that the effect of fsr mutations on biofilm formation, as well as the fsr-mediated...
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