Article
Effects of phosphate and light on growth of and bioactive peptide production by the Cyanobacterium anabaena strain 90 and its anabaenopeptilide mutant.
Applied and environmental microbiology - 1 Aug 2004
Repka Sari, Koivula Minna, Harjunpä Vesa, Rouhiainen Leo, Sivonen Kaarina
Abstract excerpt
Cyanobacteria synthesize several types of bioactive secondary metabolites. Anabaena strain 90 produces three types of bioactive peptides, microcystins (inhibitors of protein phosphatases 1 and 2A), anabaenopeptilides, and anabaenopeptins (serine protease inhibitors). To investigate the role of the anabaenopeptilides in Anabaena, wild-type strain 90 (WT) and its anabaenopeptilide deficient mutant (MU) were...
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