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PAK Kinases Ste20 and Pak1 Govern Cell Polarity at Different Stages of Mating inCryptococcus neoformans

29 Jul 2004

Abstract excerpt

Sexual identity and mating are linked to virulence of the fungal pathogen Cryptococcus neoformans. Cells of the alpha mating type are more prevalent and can be more virulent than a cells, and basidiospores are thought to be the infectious propagule. Mating in C. neoformans involves cell-cell fusion and the generation of dikaryotic hyphae, processes that involve substantial changes in cell polarity. Two...

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PMID: 15282344
DOI: 10.1091/mbc.e04-05-0370

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PAK Kinases Ste20 and Pak1 Govern Cell Polarity at Different Stages of Mating inCryptococcus neoformansPMID 15282344Read ↗

Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans.Semantic proximity Read ↗

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Conserved Elements of the RAM Signaling Pathway Establish Cell Polarity in the Basidiomycete<i>Cryptococcus neoformans</i>in a Divergent Fashion from Other FungiSemantic proximity Read ↗

Phenotypic characterization of <i>HAM1</i> , a novel mating regulator of the fungal pathogen <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth.Semantic proximity Read ↗

Function of Cryptococcus neoformans KAR7 (SEC66) in karyogamy during unisexual and opposite-sex mating.Semantic proximity Read ↗

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A homolog of Ste6, the a-factor transporter in Saccharomyces cerevisiae, is required for mating but not for monokaryotic fruiting in Cryptococcus neoformans.Semantic proximity Read ↗

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