Article
A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential.
The Journal of experimental medicine - 19 Jul 2004
Kögler Gesine, Sensken Sandra, Airey Judith A, Trapp Thorsten, Müschen Markus, Feldhahn Niklas, Liedtke Stefanie, Sorg Rüdiger V, Fischer Johannes, Rosenbaum Claudia, Greschat Susanne, Knipper Andreas, Bender Jörg, Degistirici Ozer, Gao Jizong, Caplan Arnold I, Colletti Evan J, Almeida-Porada Graça, Müller Hans W, Zanjani Esmail, Wernet Peter
Abstract excerpt
Here a new, intrinsically pluripotent, CD45-negative population from human cord blood, termed unrestricted somatic stem cells (USSCs) is described. This rare population grows adherently and can be expanded to 10(15) cells without losing pluripotency. In vitro USSCs showed homogeneous differentiation into osteoblasts, chondroblasts, adipocytes, and hematopoietic and neural cells including astrocytes and neurons...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.