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Article

Premorbid cognitive testing predicts the onset of dementia and Alzheimer's disease better than and independently of APOE genotype.

Journal of neurology, neurosurgery, and psychiatry - 1 Aug 2004

Cervilla J, Prince M, Joels S, Lovestone S, Mann A

Abstract excerpt

OBJECTIVE: To determine whether a cognitive test package can predict the onset of dementia up to 11 years later, and the extent to which this prediction is independent of that provided by APOE genotype. METHODS: Prospective cohort study based on 54 general practices in the UK; 657 survivors of the 1088 participants in the MRC treatment trial of hypertension in older adults were followed for up to 11 years; 370...

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Identifiers

PMID: 15258208
DOI: 10.1136/jnnp.2003.028076
PMCID: PMC1739178

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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