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Article

Analysis of Splice Variants of the Immediate-Early 1 Region of Human Cytomegalovirus

14 Jul 2004

Abstract excerpt

The major immediate-early (MIE) gene of human cytomegalovirus (HCMV) produces multiple mRNAs through differential splicing and polyadenylation. Reverse transcriptase PCR was used to characterize transcripts from exons 1, 2, 3, and 4 (immediate-early 1 [IE1]). The expected IE72 and IE19 mRNAs were detected, as well as two heretofore-uncharacterized transcripts designated IE17.5 and IE9. The IE72, IE19, and IE17.5...

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PMID: 15254190
DOI: 10.1128/jvi.78.15.8191-8200.2004

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