Article
Genetic signatures of pre-expansion bottleneck in the Choctaw population of Oklahoma.
American journal of physical anthropology - 1 Aug 2004
Wang Ning, Zhou Xiaodong, Tan Filemon K, Foster Morris W, Arnett Frank C, Chakraborty Ranajit
Abstract excerpt
Previous research showed that the Choctaw Indians of Oklahoma exhibit considerable linkage disequilibria (LD) in a number of regions of the genome that has allowed genetic fine mapping for potential susceptibility genes for the autoimmune connective tissue disease scleroderma, or systemic sclerosis (SSc). In principle, such enhanced background LD in the Choctaws could be caused by population bottleneck event(s)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
