Article
Who are the Okinawans? Ancestry, genome diversity, and implications for the genetic study of human longevity from a geographically isolated population.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Dec 2014
Bendjilali Nasrine, Hsueh Wen-Chi, He Qimei, Willcox D Craig, Nievergelt Caroline M, Donlon Timothy A, Kwok Pui-Yan, Suzuki Makoto, Willcox Bradley J
Abstract excerpt
Isolated populations have advantages for genetic studies of longevity from decreased haplotype diversity and long-range linkage disequilibrium. This permits smaller sample sizes without loss of power, among other utilities. Little is known about the genome of the Okinawans, a potential population isolate, recognized for longevity. Therefore, we assessed genetic diversity, structure, and admixture in Okinawans,...
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