Article
Psoriasis: a complex clinical and genetic disorder.
Current rheumatology reports - 1 Aug 2004
Valdimarsson Helgi, Karason Ari, Gudjonsson Johann E
Abstract excerpt
Psoriasis is associated with arthritis in approximately 10% of patients. The skin disease and arthritis have a strong but complex genetic component. Several susceptibility loci have been reported including one major locus that maps very close to the human leukocyte antigen-C gene on chromosome 6p. No causative gene has so far been conclusively identified. A recent genetic analysis that only included patients with...
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