Article
The role of CFTR and SPINK-1 mutations in pancreatic disorders in HIV-positive patients: a case-control study.
AIDS (London, England) - 23 Jul 2004
Felley Christian, Morris Michael A, Wonkam Ambroise, Hirschel Bernard, Flepp Markus, Wolf Katja, Furrer Hansjakob, Battegay Manuel, Bernasconi Enos, Telenti Amalio, Frossard Jean-Louis
Abstract excerpt
OBJECTIVE: Pancreatic disorders in HIV-positive patients are frequent. CFTR and SPINK-1 mutations have been reported to increase the risk of pancreatitis, but no data are available in HIV-positive patients. This study will evaluate the frequency of CFTR mutations and SPINK-1 polymorphisms in HIV-positive patients with clinical pancreatitis or asymptomatic elevation of serum pancreatic enzymes. METHOD: Cases...
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