The Lactobacillus casei ptsHI47T mutation causes overexpression of a LevR-regulated but RpoN-independent operon encoding a mannose class phosphotransferase system.

doi:10.1128/JB.186.14.4543-4555.2004

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Article

The Lactobacillus casei ptsHI47T mutation causes overexpression of a LevR-regulated but RpoN-independent operon encoding a mannose class phosphotransferase system.

Journal of bacteriology - 1 Jul 2004

Mazé Alain, Boël Grégory, Poncet Sandrine, Mijakovic Ivan, Le Breton Yoann, Benachour Abdellah, Monedero Vicente, Deutscher Josef, Hartke Axel

Abstract excerpt

A proteome analysis of Lactobacillus casei mutants that are affected in carbon catabolite repression revealed that a 15-kDa protein was strongly overproduced in a ptsHI47T mutant. This protein was identified as EIIA of a mannose class phosphotransferase system (PTS). A 7.1-kb DNA fragment containing the EIIA-encoding open reading frame and five other genes was sequenced. The first gene encodes a protein...

Topics

Amino Acid Sequence
Amino Acid Substitution
Bacterial Proteins
DNA, Bacterial
DNA-Binding Proteins
DNA-Directed RNA Polymerases
Fructose
Gene Deletion
Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Bacterial

Lacticaseibacillus casei

Mannose

Molecular Sequence Data

Mutation

Operon

Phosphoenolpyruvate Sugar Phosphotransferase System

Phosphorylation

Promoter Regions, Genetic

Source

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Identifiers

PMID: 15231787
DOI: 10.1128/JB.186.14.4543-4555.2004
PMCID: PMC438589

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