Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytotoxic and DNA‐Damaging Effects of Diterpenoid Quinones from the Roots of Salvia officinalis L. on Colonic and Hepatic Human Cells Cultured in vitro

1 Jun 2004

Abstract excerpt

Three diterpenoid quinones (royleanone- SAR 3, horminone- SAR 26, and acetyl horminone- SAR 43) isolated from the roots of Salvia officinalis L. were tested for their cytotoxic and DNA-damaging activity in human colon carcinoma cells Caco-2 and human hepatoma cells HepG2 cultured in vitro. Cytotoxicity was measured by the trypan blue exclusion technique and induction of apoptosis was evaluated by flow...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Essential Oils and Antimicrobial Activity
Share to Natural product bioactivities and synthesis
Share to Traditional Chinese Medicine Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15228500
DOI: 10.1111/j.1742-7843.2004.pto940605.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytotoxic and DNA‐Damaging Effects of Diterpenoid Quinones from the Roots of Salvia officinalis L. on Colonic and Hepatic Human Cells Cultured in vitroPMID 15228500Read ↗

White tea (Camellia sinensis) inhibits proliferation of the colon cancer cell line, HT-29, activates caspases and protects DNA of normal cells against oxidative damageSemantic proximity Read ↗

Anticancer effect of black tea extract in human cancer cell linesSemantic proximity Read ↗

Apoptosis induction in ascorbic acid treated human colorectal cancer cell lines (Caco-2)Semantic proximity Read ↗

Cytotoxic effects of flavonoids against a human colon cancer derived cell line, COLO 201: A potential natural anti-cancer substanceSemantic proximity Read ↗

Ellagitannins from Rubus idaeus L. Exert Geno- and Cytotoxic Effects against Human Colon Adenocarcinoma Cell Line Caco-2Semantic proximity Read ↗

Deoxycholate induces DNA damage and apoptosis in human colon epithelial cells expressing either mutant or wild-type p53.Semantic proximity Read ↗

In vitro Cytogenetic Effects of the Euphorbia grisophylla Aerial Parts Aqueous Extract in Human Peripheral LymphocytesSemantic proximity Read ↗

Induction of apoptosis on human hepatocarcinoma cell lines by an alkyl resorcinol isolated from Lithraea molleoides.Semantic proximity Read ↗

Hemoglobin and hemin induce DNA damage in human colon tumor cells HT29 clone 19A and in primary human colonocytes.Semantic proximity Read ↗

Modulation of oxidative cell damage by reconstituted mixtures of phenolic apple juice extracts in human colon cell linesSemantic proximity Read ↗

The effect of five artificial sweeteners on Caco-2, HT-29 and HEK-293 cellsSemantic proximity Read ↗

Modulation ofras p21 oncoprotein levels and DNA strand breakage in human cells with chemotherapeutic agents and/or deferoxamineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.