Article
Understanding HIV-1 drug resistance.
Therapeutic drug monitoring - 1 Apr 2004
Frenkel Lisa M, Tobin Nicole H
Abstract excerpt
Infection with drug-resistant HIV-1 may result from the acquisition of mutant strains or from their selection within the individual; either can compromise the efficacy of antiretroviral therapy (ART). Drug-resistance testing is recommended to assist in the choice of ART. Herein, factors that contribute to the selection of drug-resistant virus and details important to the interpretation of the genotypic and...
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