Article
Contribution of exotoxin A of Pseudomonas aeruginosa in acute and chronic experimental renal infection.
Japanese journal of infectious diseases - 1 Jun 2004
Sharma Saroj, Kaur Ramanjeet, Yadav Vanashree, Harjai Kusum, Joshi Kusum
Abstract excerpt
The role of Pseudomonas aeruginosa exotoxin A was studied in acute and chronic pyelonephritis models employing an exotoxin A-producing strain PAO, and its toxin deficient mutant PAOT1. Interestingly, the mutant strain was found to be at an advantage in its ability to induce acute pyelonephritis and it induced severer renal pathology. No significant differences were observed in the ability of the parent strain and...
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