Article
Adult-derived liver stem cells acquire a cardiomyocyte structural and functional phenotype ex vivo.
The American journal of pathology - 1 Jul 2004
Muller-Borer Barbara J, Cascio Wayne E, Anderson Page A W, Snowwaert John N, Frye James R, Desai Niyati, Esch Gwyn L, Brackham Joe A, Bagnell C Robert, Coleman William B, Grisham Joe W, Malouf Nadia N
Abstract excerpt
We examined the differentiation potential of an adult liver stem cell line (WB F344) in a cardiac microenvironment, ex vivo. WB F344 cells were established from a single cloned nonparenchymal epithelial cell isolated from a normal male adult rat liver. Genetically modified, WB F344 cells that express beta-galactosidase and green fluorescent protein or only beta-galactosidase were co-cultured with dissociated rat...
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