Article
Arterial stiffness and angiotensinogen gene in hypertensive patients and mutant mice.
Journal of hypertension - 1 Jul 2004
Bozec Erwan, Lacolley Patrick, Bergaya Sonia, Boutouyrie Pierre, Meneton Pierre, Herissé-Legrand Monique, Boulanger Chantal M, Alhenc-Gelas François, Kim Hyung-Suk, Laurent Stéphane, Dabiré Hubert
Abstract excerpt
OBJECTIVE: To determine whether carotid artery stiffness was increased in patients with untreated essential hypertension who are homozygous for the T allele of the M235T polymorphism of the angiotensinogen (AGT) gene and in mutant mice carrying three copies of the angiotensinogen (Agt) gene. METHODS: Using echotracking systems, we studied carotid mechanical properties in 98 never-treated hypertensive patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
