Article
Compliance and pulse wave velocity assessed by MRI detect early aortic impairment in young patients with mutation of the smooth muscle myosin heavy chain.
Journal of magnetic resonance imaging : JMRI - 1 Nov 2008
Lalande A, Khau Van Kien P, Walker P M, Zhu L, Legrand L, Claustres M, Jeunemaître X, Brunotte F, Wolf J E
Abstract excerpt
PURPOSE: To evaluate aortic elasticity with MRI on young asymptomatic individuals with mutation of the smooth muscle myosin heavy chain in whom aortic enlargement is not present. MATERIALS AND METHODS: Aortic compliance, aortic distensibility, and pulse wave velocity (PWV) were semiautomatically measured from MRI in 8 asymptomatic subjects having a mutation of the MYH11 gene (M+) and 21 nonmutated relatives (M-)...
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