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Article

Virulence potential of the staphylococcal adhesin CNA in experimental arthritis is determined by its affinity for collagen.

The Journal of infectious diseases - 15 Jun 2004

Xu Yi, Rivas Jorge M, Brown Eric L, Liang Xiaowen, Höök Magnus

Abstract excerpt

BACKGROUND: Staphylococcus aureus is a major cause of bacterial arthritis, which often results in severe joint damage. CNA, a collagen adhesin of S. aureus, was shown to be a virulence factor in several animal models. However, the precise molecular mechanism by which CNA contributes to virulence remains unclear. METHODS: We examined the role of the collagen-binding function of CNA in a mouse model of septic...

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Identifiers

PMID: 15181582
DOI: 10.1086/420851

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ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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