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Article

Staphylococcus aureus collagen adhesin contributes to the pathogenesis of osteomyelitis.

Bone - 1 Jan 2002

Elasri M O, Thomas J R, Skinner R A, Blevins J S, Beenken K E, Nelson C L, Smeltzer M S

Abstract excerpt

To evaluate the role of the Staphylococcus aureus collagen-binding adhesin (Cna) in bone and joint infection, we generated a cna mutant in S. aureus UAMS-1, a strain that was originally isolated from the bone of a patient suffering from osteomyelitis. The mutant (UAMS-237) was unable to bind collagen but bound fibronectin at levels comparable to UAMS-1. The relative virulence of UAMS-1 and UAMS-237 was assessed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11792597
DOI: 10.1016/s8756-3282(01)00632-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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