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A Novel Interaction of Staphylococcal Protein A With Human Fibronectin and Its Implications in Host Cell Adhesion

31 May 2025

Abstract excerpt

ABSTRACT Staphylococcus aureus is the causative agent of serious human health conditions, such as sepsis, endocarditis, and necrotizing pneumonia, as well as less severe clinical manifestations including epithelial and mucosal infections. This pathogen expresses a wide range of surface virulence factors, among which fibronectin‐binding proteins play a crucial role in both bacterial adhesion and infection of host...

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PMID: 40448417
DOI: 10.1096/fj.202500086r

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