Article
Association of the T45G polymorphism in exon 2 of the adiponectin gene with polycystic ovary syndrome: role of Delta4-androstenedione.
Human reproduction (Oxford, England) - 1 Aug 2004
Panidis Dimitrios, Kourtis Anargyros, Kukuvitis Asterios, Farmakiotis Dimitrios, Xita Nectaria, Georgiou Ioannis, Tsatsoulis Agathocles
Abstract excerpt
BACKGROUND: Insulin resistance is a prominent feature of polycystic ovary syndrome (PCOS), independent of obesity. It is possible that insulin resistance in PCOS is genetically determined. Adiponectin is a protein that modulates insulin action and is regarded as a possible link between adiposity and insulin resistance. The objective of this study was to examine the role of the adiponectin gene T45G polymorphism,...
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