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Article

Genotoxicity of hormonal steroids.

Toxicology letters - 15 Jun 2004

Joosten H F P, van Acker F A A, van den Dobbelsteen D J, Horbach G J M J, Krajnc E I

Abstract excerpt

Hormonal steroids have a widespread use in medicine and their side effects are continuously debated. The possible genotoxic activity of steroids has been the subject of many investigations. The natural estrogens estradiol, estrone and estriol are generally negative in the ICH core battery of tests, but several positive results have been obtained when using additional endpoints of genotoxicity. The genotoxic...

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Identifiers

PMID: 15177647
DOI: 10.1016/j.toxlet.2004.01.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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