A gravitational hypothesis of essential hypertension as a natural adaptation to increased gravitational stress caused by regular, prolonged sitting typical of modern life.

Abstract excerpt

BACKGROUND: Spaceflight studies have demonstrated that adaptation to increased gravitational stress after prolonged microgravity includes sympathetic activation, water retention, and arterial pressure increase, i.e. is very similar to essential hypertension, which looks like an advanced stage of adaptation to a further increase in gravitational stress. MATERIAL/METHODS: Theoretical analysis and literature review...

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