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Transgenic mouse models of Alzheimer's disease: how useful have they been for therapeutic development?

Briefings in functional genomics & proteomics - 1 Apr 2004

Duff Karen, Suleman Faraha

Abstract excerpt

Transgenic mice have been created in an attempt to generate models of human Alzheimer's disease, but success has been partial and unpredictable. The overall aim of this paper is to illustrate how genomics can be used in translational research, turning genetic information in the form of pathogenic mutations into clinically useful drugs against a major human disease. This paper will illustrate how genetic...

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PMID: 15163359
DOI: 10.1093/bfgp/3.1.47

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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