Article
Chromosomal radiosensitivity and low penetrance predisposition to cancer.
Cytogenetic and genome research - 1 Jan 2004
Scott D
Abstract excerpt
This mini-review summarises studies in this Institute on the sensitivity of cells of patients with common cancers to the chromosome-damaging effects of ionising radiation, in the context of related studies. Using the 90th percentile of healthy controls (n >200) as the cut-off point between a normal and a sensitive response, 40% of patients with breast cancer (n = 166) were sensitive when cells were irradiated in...
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