Article
Modeling the Qo site of crop pathogens in Saccharomyces cerevisiae cytochrome b.
European journal of biochemistry - 1 Jun 2004
Fisher Nicholas, Brown Amanda C, Sexton Graham, Cook Alison, Windass John, Meunier Brigitte
Abstract excerpt
Saccharomyces cerevisiae has been used as a model system to characterize the effect of cytochrome b mutations found in fungal and oomycete plant pathogens resistant to Q(o) inhibitors (QoIs), including the strobilurins, now widely employed in agriculture to control such diseases. Specific residues in the Q(o) site of yeast cytochrome b were modified to obtain four new forms mimicking the Q(o) binding site of...
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