Demonstration of sequence variations in the promoter region of the human cystatin C gene.

doi:10.1515/bchm3.1992.373.2.471

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Article

Demonstration of sequence variations in the promoter region of the human cystatin C gene.

Biological chemistry Hoppe-Seyler - 1 Jul 1992

Balbin M, Grubb A, Abrahamson M

Abstract excerpt

Four point mutations in the promoter region of the human cystatin C gene have been detected by direct sequencing of polymerase chain reaction (PCR) amplified DNA. The four base changes are all localized within a short segment of 85 base pairs. Three cystatin C gene alleles could be defined with r...

Topics

Base Sequence
Cloning, Molecular
Cystatin C
Cystatins
DNA, Recombinant
Electrophoresis, Agar Gel
Gene Amplification
Molecular Sequence Data
Mutation
Oligonucleotides
Polymerase Chain Reaction
Polymorphism, Genetic
Promoter Regions, Genetic

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