Article
Single nucleotide polymorphism (SNP) discovery in mammals: a targeted-gene approach.
Molecular ecology - 1 Jun 2004
Aitken Nicola, Smith Steven, Schwarz Carsten, Morin Phillip A
Abstract excerpt
Single nucleotide polymorphisms (SNPs) have rarely been exploited in nonhuman and nonmodel organism genetic studies. This is due partly to difficulties in finding SNPs in species where little DNA sequence data exist, as well as to a lack of robust and inexpensive genotyping methods. We have explored one SNP discovery method for molecular ecology, evolution, and conservation studies to evaluate the method and its...
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