Article
Circadian variations of bone marrow engraftability.
Journal of cellular physiology - 1 Jul 2004
D'Hondt Lionel, McAuliffe Christina, Damon Jeffrey, Reilly Judith, Carlson Jane, Dooner Mark, Colvin Gerald, Lambert Jean-François, Hsieh Chung-Cheng, Habibian Houri, Stencel Kimberly, Quesenberry Peter J
Abstract excerpt
Circadian rhythms exist for hematopoiesis, but little is known about circadian variation of bone marrow engraftability and host "acceptability". Using a B6.SJL to C57BL/6J congenic transplant model, we chose 3-times with light on: Hours After Light Onset (HALO) 4, 8, and 12 and 3-times with light off: HALO 16, 20, and 24. The mice were conditioned on a 12-h light/dark cycles. Recipient mice (100 cGy) received 40...
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