Article
Liver biopsy discloses a new apolipoprotein A-I hereditary amyloidosis in several unrelated Italian families.
Gastroenterology - 1 May 2004
Obici Laura, Palladini Giovanni, Giorgetti Sofia, Bellotti Vittorio, Gregorini Gina, Arbustini Eloisa, Verga Laura, Marciano Sabrina, Donadei Simona, Perfetti Vittorio, Calabresi Laura, Bergonzi Cesare, Scolari Francesco, Merlini Giampaolo
Abstract excerpt
BACKGROUND & AIMS: Hereditary systemic amyloidoses are autosomal dominant, late-onset disorders caused by mutations in the genes for a group of plasma proteins including transthyretin, lysozyme, fibrinogen Aalpha chain, gelsolin, apolipoprotein A-I, and apolipoprotein A-II. We investigated both phenotypic and genotypic aspects of apolipoprotein A-I amyloidosis unexpectedly disclosed by liver biopsy in 13...
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