Embryonic expression of the human <i>MID1</i> gene and its mutations in Opitz syndrome

Abstract excerpt

<h3>Background</h3> The systemic diseases of connective tissue have autoimmune mechanism in development. While autoimmunity involves adaptive immune activation, autoinflammation involves innate immune activation. The prototype of autoinflammatory diseases is familial Mediterranean fever (FMF), which is the global medical problem for Armenian ethnos on the whole, affecting 1–2% of population. <h3>Objectives</h3>...

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