Article
Limited genetic diversity in polynesians reflected in the highly polymorphic 3'HVR alpha-globin gene marker.
Human heredity - 1 Jan 1992
Hertzberg M S, Mickleson K N, Trent R J
Abstract excerpt
Polynesians from five distinct island groups were studied with DNA probe alpha 3'HVR, a highly polymorphic VNTR (variable number of tandem repeats) minisatellite region associated with the alpha-globin gene cluster. Results showed a paucity of genetic heterozygosity together with clustering of alpha 3'HVR alleles with alpha-globin DNA haplotypes and alpha-globin gene rearrangements. This restricted diversity is...
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