Islet cell antibody heterogeneity among type 1 (insulin-dependent) diabetic patients.

doi:10.1007/BF00429102

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Article

Islet cell antibody heterogeneity among type 1 (insulin-dependent) diabetic patients.

Diabetologia - 1 Aug 1992

Timsit J, Caillat-Zucman S, Blondel H, Chédin P, Bach J F, Boitard C

Abstract excerpt

Conventional detection of islet cell antibodies is based on indirect immunofluorescence performed on frozen human pancreas sections. The number and nature of epitopes recognized by antibodies detected by such techniques are unknown. To determine the existence of heterogeneous fluorescence pattern...

Topics

Adult
Alleles
Autoantibodies
Diabetes Mellitus, Type 1
Female
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
HLA-DR Antigens
Histocompatibility Testing
Humans
Islets of Langerhans
Male
Microscopy, Fluorescence

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