Article
Islet cell antibody heterogeneity among type 1 (insulin-dependent) diabetic patients.
Diabetologia - 1 Aug 1992
Timsit J, Caillat-Zucman S, Blondel H, Chédin P, Bach J F, Boitard C
Abstract excerpt
Conventional detection of islet cell antibodies is based on indirect immunofluorescence performed on frozen human pancreas sections. The number and nature of epitopes recognized by antibodies detected by such techniques are unknown. To determine the existence of heterogeneous fluorescence patterns of islet cell antibodies on pancreatic sections, we selected two sera showing a distinctive granular fluorescence. We...
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