Minor Transplacental Passage of Fondaparinux in Vivo

doi:10.1056/nejm200404293501825

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Article

Minor Transplacental Passage of Fondaparinux in Vivo

28 Apr 2004

Abstract excerpt

To the Editor: Low-molecular-weight heparin remains the anticoagulant of choice for pregnant women with previous thromboembolic events. Fondaparinux (Arixtra, Sanofi-Synthelabo) is a chemically synthesized derivative of the natural pentasaccharide sequence that mediates the interaction of heparin with antithrombin.1 It has been recommended for prophylaxis against thromboembolism after hip or knee surgery.2,3 My...

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Share to Blood Coagulation and Thrombosis Mechanisms
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PMID: 15115845
DOI: 10.1056/nejm200404293501825

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