Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis.

BMC genetics - 25 Feb 2004

Dvornyk Volodymyr, Long Ji-Rong, Xiong Dong-Hai, Liu Peng-Yuan, Zhao Lan-Juan, Shen Hui, Zhang Yuan-Yuan, Liu Yong-Jun, Rocha-Sanchez Sonia, Xiao Peng, Recker Robert R, Deng Hong-Wen

Abstract excerpt

BACKGROUND: Public SNP databases are frequently used to choose SNPs for candidate genes in the association and linkage studies of complex disorders. However, their utility for such studies of diseases with ethnic-dependent background has never been evaluated. RESULTS: To estimate the accuracy and completeness of SNP public databases, we analyzed the allele frequencies of 41 SNPs in 10 candidate genes for obesity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Nucleic Acid

Share to Family Health

Share to Hispanic or Latino

Share to Obesity

Share to Osteoporosis

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 15113403
DOI: 10.1186/1471-2156-5-4
PMCID: PMC395827

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis.PMID 15113403Read ↗

Genome-wide evaluation of the public SNP databases.Semantic proximity Read ↗

Experimental validation of data mined single nucleotide polymorphisms from several databases and consecutive dbSNP builds.Semantic proximity Read ↗

Single nucleotide polymorphism identification in candidate gene systems of obesity.Semantic proximity Read ↗

Candidate single nucleotide polymorphism selection using publicly available tools: a guide for epidemiologists.Semantic proximity Read ↗

Single-nucleotide polymorphisms in the public domain: how useful are they?Semantic proximity Read ↗

Single nucleotide polymorphisms in bone turnover-related genes in Koreans: ethnic differences in linkage disequilibrium and haplotype.Semantic proximity Read ↗

Replication study of candidate genes/loci associated with osteoporosis based on genome-wide screening.Semantic proximity Read ↗

Association analysis of vitamin D-binding protein gene polymorphisms with variations of obesity-related traits in Caucasian nuclear families.Semantic proximity Read ↗

Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes.Semantic proximity Read ↗

Estimation of carrier frequency of a 2.7 kb deletion allele of the P gene associated with OCA2 in African-Americans.Semantic proximity Read ↗

On genome-wide association studies and their meta-analyses: lessons learned from osteoporosis studies.Semantic proximity Read ↗

Significant association between body composition phenotypes and the osteocalcin genomic region in normative human population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.