Article
Association of vitamin D and estrogen receptor gene polymorphism with the effects of longterm hormone replacement therapy on bone mineral density.
Journal of bone and mineral metabolism - 1 Jan 2004
Kurabayashi Takumi, Matsushita Hiroshi, Tomita Masatoshi, Kato Nozomi, Kikuchi Mariko, Nagata Hiroshi, Honda Akira, Yahata Tetsuro, Tanaka Kenichi
Abstract excerpt
We longitudinally studied whether vitamin D receptor (VDR) and estrogen receptor (ER) gene polymorphisms in Japanese women influenced the effect of longterm hormone replacement therapy (HRT) on bone mineral density (BMD) in the lumbar spine. The 81 subjects were aged 40 to 64 years (mean +/- SEM, 49.5 +/- 0.6 years), and had received sequential or continuous HRT regimens, including 0.625 mg of conjugated equine...
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