Article
Association of estrogen receptor alpha gene microsatellite polymorphism with annual changes in bone mineral density in Korean women with hormone replacement therapy.
Journal of bone and mineral metabolism - 1 Jan 2005
Yim Chang Hoon, Choi Jong Tae, Choi Hyun Ah, Kang Young Soon, Moon In Gul, Yoon Hyun Koo, Han In Kwon, Kang Dae Hee, Han Ki Ok
Abstract excerpt
Variation in drug response to hormone replacement therapy (HRT) may reflect genetic heterogeneity in the estrogen-related genes, possibly including estrogen receptor alpha (ERalpha) gene. However, only a few association studies of the drug response to HRT have been reported, focusing mainly on the intronic polymorphisms of the ERalpha gene. We therefore examined 284 postmenopausal women (mean age, 52.2 +/- 5.0...
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