Article
High genetic stability of TM1 and TM2 strains of subtype B feline immunodeficiency virus in long-term infection.
The Journal of veterinary medical science - 1 Mar 2004
Ikeda Yasuhiro, Miyazawa Takayuki, Nishimura Yorihiro, Nakamura Kazuya, Tohya Yukinobu, Mikami Takeshi
Abstract excerpt
To know the genetic changes of feline immunodeficiency virus (FIV) in long-term infection in cats, we inoculated three specific pathogen-free cats with FIV isolates and determined a partial env sequence covering the V3-V5 region. In 2 cats infected with subtype B strains TM1 and TM2, only one amino acid change in region V3 was observed at 9 years post infection (y.p.i.), and no nucleotide substitutions were...
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