Article
Genetic and molecular evidence for a trans-acting regulatory locus controlling glutathione S-transferase-2 expression in Aedes aegypti.
Molecular & general genetics : MGG - 1 Aug 1992
Grant D F, Hammock B D
Abstract excerpt
The amount of glutathione S-transferase-2 (GST-2) protein and enzyme activity in a mutant strain (strain GG) of the yellow fever mosquito (Aedes aegypti) is approximately 25-fold higher than in the wild-type (++) strain. The mode of inheritance of the GG phenotype was studied in F1 and backcross progeny using GST enzyme assays, isozyme-specific antisera, and Northern blot analysis. Enzyme assay of parental and F1...
Topics
- Aedes
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Cloning, Molecular
- Gene Expression Regulation, Enzymologic
- Genes, Regulator
- Glutathione Transferase
- Immunoblotting
- Insecticide Resistance