Article
Association of Meiotic Arrest with Lack ofBOULEProtein Expression in Infertile Men
1 Apr 2004
Abstract excerpt
Spermatogenesis is a complex developmental process of mitotic and meiotic cell divisions that ultimately results in production of haploid spermatozoa. Recent studies in flies demonstrate that the BOULE gene encodes a key factor of meiosis in male germ cells, regulating the expression of twine, a cdc25 phosphatase, which promotes progression through meiosis. In this study, we investigated whether a common...
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