Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Folate and DNA Methylation: A Mechanistic Link between Folate Deficiency and Colorectal Cancer?

1 Apr 2004

Abstract excerpt

Epidemiological, clinical, and animal studies collectively indicate that dietary folate intake and blood folate levels are inversely associated with colorectal cancer risk. Folate plays an essential role in one-carbon transfer involving remethylation of homocysteine to methionine, which is a precursor of S-adenosylmethionine, the primary methyl group donor for most biological methylations. DNA methylation is an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Folate and B Vitamins Research
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15066913
DOI: 10.1158/1055-9965.511.13.4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Folate and DNA Methylation: A Mechanistic Link between Folate Deficiency and Colorectal Cancer?PMID 15066913Read ↗

Nutritional epigenetics: impact of folate deficiency on DNA methylation and colon cancer susceptibility.Semantic proximity Read ↗

Folate, colorectal cancer and the involvement of DNA methylationSemantic proximity Read ↗

Folate, colorectal carcinogenesis, and DNA methylation: Lessons from animal studiesSemantic proximity Read ↗

Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesisSemantic proximity Read ↗

Folate and DNA MethylationSemantic proximity Read ↗

Epidemiologic studies of folate and colorectal neoplasia: a review.Semantic proximity Read ↗

Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study.Semantic proximity Read ↗

Folic acid deficiency and cancer: mechanisms of DNA instabilitySemantic proximity Read ↗

Folate Deficiency Alters Hepatic and Colon MGMT and OGG-1 DNA Repair Protein Expression in Rats but Has No Effect on Genome-Wide DNA MethylationSemantic proximity Read ↗

Folate and DNA Methylation: A Review of Molecular Mechanisms and the Evidence for Folate's RoleSemantic proximity Read ↗

Nutrigenetics in cancer research--folate metabolism and colorectal cancer.Semantic proximity Read ↗

Bacterial folate biosynthesis and colorectal cancer risk: more than just a gut feelingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.