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Chorionic villus sampling (CVS) and fluorescence <i>in situ</i> hybridization (FISH) for a rapid first‐trimester prenatal diagnosis

23 Mar 2004

Abstract excerpt

OBJECTIVES: Early diagnosis of unbalanced chromosomal abnormalities can be crucial in minimizing the trauma caused by an elective abortion. Chorionic villus sampling (CVS) can be performed from 9 weeks of gestation. However, two major problems are encountered in fetal karyotyping using cultured cells from chorionic villi: the relatively slow growth of these cells in culture, which delays the diagnosis, and the...

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PMID: 15065097
DOI: 10.1002/pd.845

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