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Article

Chromosomal anomalies in early spontaneous abortions: interphase FISH analysis on 855 FFPE first trimester abortions

30 Dec 2015

Abstract excerpt

OBJECTIVE: Cytogenetic analysis of spontaneous abortuses presents at least two main challenges, cell culture failure, and excess of normal female karyotypes related to maternal cell contamination (MCC). Molecular cytogenetic techniques using uncultured cell suspension overcome cell culture failure, but do not resolve MCC at all. The aim of the present study is to demonstrate that interphase fluorescence in situ...

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Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics
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PMID: 26716606
DOI: 10.1002/pd.4768

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