Article
Culture characterization of differentiated high endothelial venule cells from human tonsils.
Laboratory investigation; a journal of technical methods and pathology - 1 Mar 1999
Baekkevold E S, Jahnsen F L, Johansen F E, Bakke O, Gaudernack G, Brandtzaeg P, Haraldsen G
Abstract excerpt
High endothelial venules (HEV) are specialized vessels that support abundant lymphocyte emigration from peripheral blood into secondary lymphoid organs. HEV endothelial cells (HEVEC) exhibit particular structural and functional features, including secretion of the HEV-specific extracellular matrix protein hevin and an array of uniquely glycosylated counter-receptors for L-selectin expressed on lymphocytes. These...
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