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Article

Viroid-induced RNA silencing of GFP-viroid fusion transgenes does not induce extensive spreading of methylation or transitive silencing.

The Plant journal : for cell and molecular biology - 1 Apr 2004

Vogt Ulrike, Pélissier Thierry, Pütz Arno, Razvi Fareha, Fischer Rainer, Wassenegger Michael

Abstract excerpt

Viroid infection is associated with the production of short interfering RNAs (siRNAs), a hallmark of post-transcriptional gene silencing (PTGS). However, viroid RNAs autonomously replicating in the nucleus have not been shown to trigger the degradation of homologous RNA in the cytoplasm. To investigate the potential of viroids for the induction of gene silencing, non-infectious fragments of potato spindle tuber...

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PMID: 15053764
DOI: 10.1111/j.1365-313X.2004.02029.x

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