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Article

Compound mutations: a common cause of severe long-QT syndrome.

Circulation - 20 Apr 2004

Westenskow Peter, Splawski Igor, Timothy Katherine W, Keating Mark T, Sanguinetti Michael C

Abstract excerpt

BACKGROUND: Long QT syndrome (LQTS) predisposes affected individuals to sudden death from cardiac arrhythmias. Although most LQTS individuals do not have cardiac events, significant phenotypic variability exists within families. Probands can be very symptomatic. The mechanism of this phenotypic v...

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PMID: 15051636
DOI: 10.1161/01.CIR.0000125524.34234.13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15051636-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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