Article
Generation, purification and functional characterization of three C3a anaphylatoxins in rainbow trout: role in leukocyte chemotaxis and respiratory burst.
Developmental and comparative immunology - 1 Jun 2004
Rotllant J, Parra D, Peters R, Boshra H, Sunyer J O
Abstract excerpt
Activation of the complement system leads to cleavage of the C3 molecule into C3b and C3a fragments. The C3a fragment plays a major role in immunity by inducing chemotaxis of eosinophils and mast cells and stimulating the respiratory burst in leukocytes. Although this anaphylotoxin has been well...
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