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Article

Loss of BMP2, Smad8, and Smad4 expression in prostate cancer progression.

The Prostate - 15 May 2004

Horvath Lisa G, Henshall Susan M, Kench James G, Turner Jennifer J, Golovsky David, Brenner Phillip C, O'Neill Gordon F, Kooner Raji, Stricker Phillip D, Grygiel John J, Sutherland Robert L

Abstract excerpt

BACKGROUND: The role of the bone morphogenetic protein (BMP) pathway in prostate cancer (PC) is unclear. This study aimed to characterize aspects of the BMP pathway in PC by assessing BMP2, Smad8, and Smad4 expression in normal, hyperplastic, and malignant prostate tissue, and to correlate findings with progression to PC. METHODS: Radical prostatectomy (RP) specimens from 74 patients with clinically localized PC...

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Source

Identifiers

PMID: 15042598
DOI: 10.1002/pros.10361

Genes

BMP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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