Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Radiation-induced up-regulation of Mmp2 involves increased mRNA stability, redox modulation, and MAPK activation.

Radiation research - 1 Apr 2004

Zhao Weiling, Goswami Prabhat C, Robbins Mike E C

Abstract excerpt

We have previously observed time- and dose-dependent increases in matrix metalloproteinase 2 (Mmp2) protein levels in rat tubule epithelial cells (NRK52E) after irradiation. However, the mechanism(s) involved remains unclear. In the present study, irradiating NRK52E cells with 0-20 Gy gamma rays was associated with time- and dose-dependent increases in Mmp2 mRNA. Studies using the transcription inhibitor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Butadienes
Share to Dactinomycin
Share to Flavonoids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Tubules

Share to Matrix Metalloproteinase 2

Share to Mitogen-Activated Protein Kinase 1

Share to Mitogen-Activated Protein Kinase 3

Share to Puromycin

Source

Identifiers

PMID: 15038770
DOI: 10.1667/3155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Radiation-induced up-regulation of Mmp2 involves increased mRNA stability, redox modulation, and MAPK activation.PMID 15038770Read ↗

Ionizing Radiation-Induced Oxidative Stress Alters miRNA ExpressionSemantic proximity Read ↗

Nrf2 alleviates radiation-induced rectal injury by inhibiting of necroptosisSemantic proximity Read ↗

Ionizing Radiation Activates the Nrf2 Antioxidant ResponseSemantic proximity Read ↗

Gamma-irradiation induces matrix metalloproteinase II expression in a p53-dependent mannerSemantic proximity Read ↗

The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit.Semantic proximity Read ↗

Effects of DNMT and MEK inhibitors on the expression of RECK, MMP-9, -2, uPA and VEGF in response to arsenite stimulation in human uroepithelial cellsSemantic proximity Read ↗

ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapySemantic proximity Read ↗

Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs.Semantic proximity Read ↗

UVA-mediated down-regulation of MMP-2 and MT1-MMP coincides with impaired angiogenic phenotype of human dermal endothelial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.